PARP1 inactivation increases regulatory T / Th17 cell proportion in intestinal inflammation. Role of HMGB1, Vitali, Roberta, Novelli Flavia, Palone Francesca, Cucchiara S., Stronati L., and Pioli Claudio , Immunology Letters, Volume 270, (2024)

PARP1 Activation Induces HMGB1 Secretion Promoting Intestinal Inflammation in Mice and Human Intestinal Organoids, Vitali, Roberta, Mancuso A.B., Palone Francesca, Pioli Claudio, Cesi Vincenzo, Negroni Anna, Cucchiara S., Oliva S., Carissimi C., Laudadio I., et al. , International Journal of Molecular Sciences, Volume 24, Number 8, (2023)

ZNF281 Promotes Colon Fibroblast Activation in TGFβ1-Induced Gut Fibrosis, Laudadio, I., Bastianelli A., Fulci V., Carissimi C., Colantoni Eleonora, Palone Francesca, Vitali Roberta, Lorefice E., Cucchiara S., Negroni Anna, et al. , International Journal of Molecular Sciences, Volume 23, Number 18, (2022)

Fecal High-Mobility Group Box 1 as a Marker of Early Stage of Necrotizing Enterocolitis in Preterm Neonates, Vitali, Roberta, Terrin G., Palone Francesca, Laudadio I., Cucchiara S., Boscarino G., Di Chiara M., and Stronati L. , Frontiers in Pediatrics, Volume 9, (2021)

Necroptosis in intestinal inflammation and cancer: New concepts and therapeutic perspectives, Negroni, Anna, Colantoni Eleonora, Cucchiara S., and Stronati Laura , Biomolecules, Volume 10, Issue 10, Number 10, p.1-20, (2020)

Functional analysis of gut microbiota and immunoinflammation in children with autism spectrum disorders, Carissimi, C., Laudadio I., Palone Francesca, Fulci V., Cesi Vincenzo, Cardona F., Alfonsi C., Cucchiara S., Isoldi S., and Stronati L. , Digestive and Liver Disease, Volume 51, Number 10, p.1366-1374, (2019)

NOD2 and inflammation: Current insights, Negroni, Anna, Pierdomenico Maria, Cucchiara S., and Stronati L. , Journal of Inflammation Research, Volume 11, p.49-60, (2018)

Transcription Factor ZNF281: A Novel Player in Intestinal Inflammation and Fibrosis, Pierdomenico, Maria, Palone Francesca, Cesi Vincenzo, Vitali Roberta, Mancuso A.B., Cucchiara S., Oliva S., Aloi M., and Stronati L. , Frontiers in immunology, Volume 9, p.2907, (2018)

RIP3 AND pMLKL promote necroptosis-induced inflammation and alter membrane permeability in intestinal epithelial cells, Negroni, Anna, Colantoni Eleonora, Pierdomenico Maria, Palone Francesca, Costanzo Manuela, Oliva S., Tiberti A., Cucchiara S., and Stronati L. , Digestive and Liver Disease, Volume 49, Number 11, p.1201-1210, (2017)

Fecal HMGB1 reveals microscopic inflammation in adult and pediatric patients with inflammatory bowel disease in clinical and endoscopic remission, Palone, Francesca, Vitali Roberta, Cucchiara S., Mennini M., Armuzzi A., Pugliese D., D'incà R., Barberio B., and Stronati L. , Inflammatory Bowel Diseases, Volume 22, Number 12, p.2886-2893, (2016)

The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase, Haile, P.A., Votta B.J., Marquis R.W., Bury M.J., Mehlmann J.F., Singhaus R., Charnley A.K., Lakdawala A.S., Convery M.A., Lipshutz D.B., et al. , Journal of Medicinal Chemistry, Volume 59, Number 10, p.4867-4880, (2016)

Krill oil reduces intestinal inflammation by improving epithelial integrity and impairing adherent-invasive Escherichia coli pathogenicity, Costanzo, Manuela, Cesi Vincenzo, Prete E., Negroni Anna, Palone Francesca, Cucchiara S., Oliva S., Leter B., and Stronati L. , Digestive and Liver Disease, Volume 48, Number 1, p.34-42, (2016)

NOD2 induces autophagy to control AIEC bacteria infectiveness in intestinal epithelial cells, Negroni, Anna, Colantoni Eleonora, Vitali Roberta, Palone Francesca, Pierdomenico Maria, Costanzo Manuela, Cesi Vincenzo, Cucchiara S., and Stronati L. , Inflamm Res, 2016 Oct, Volume 65, Issue 10, p.803-13, (2016)

NOD2 Is Regulated by MIR-320 in Physiological Conditions but this Control Is Altered in Inflamed Tissues of Patients with Inflammatory Bowel Disease, Pierdomenico, Maria, Cesi Vincenzo, Cucchiara S., Vitali Roberta, Prete E., Costanzo Manuela, Aloi M., Oliva S., and Stronati L. , Inflammatory Bowel Diseases, Volume 22, Number 2, p.315-326, (2016)

Apoptosis, necrosis, and necroptosis in the gut and intestinal homeostasis, Negroni, Anna, Cucchiara S., and Stronati L. , Mediators of Inflammation, Volume 2015, (2015)

Dipotassium glycyrrhizate via HMGB1 or AMPK signaling suppresses oxidative stress during intestinal inflammation, Vitali, Roberta, Palone Francesca, Pierdomenico Maria, Negroni Anna, Cucchiara S., Aloi M., Oliva S., and Stronati L. , Biochemical Pharmacology, Volume 97, Number 3, p.292-299, (2015)

Endoplasmic reticulum stress and unfolded protein response are involved in paediatric inflammatory bowel disease, Negroni, Anna, Prete E., Vitali Roberta, Cesi Vincenzo, Aloi M., Civitelli F., Cucchiara S., and Stronati L. , Digestive and Liver Disease, Volume 46, Number 9, p.788-794, (2014)

Lactoferrin prevents invasion and inflammatory response following E. coli strain LF82 infection in experimental model of Crohn's disease, Bertuccini, L., Costanzo Manuela, Iosi F., Tinari A., Terruzzi F., Stronati L., Aloi M., Cucchiara S., and Superti F. , Digestive and Liver Disease, Volume 46, Number 6, p.496-504, (2014)

Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation, Pierdomenico, Maria, Negroni Anna, Stronati L., Vitali Roberta, Prete E., Bertin J., Gough P.J., Aloi M., and Cucchiara S. , American Journal of Gastroenterology, Volume 109, Number 2, p.279-287, (2014)

Plasma high mobility group box 1 protein reflects fibrosis in pediatric nonalcoholic fatty liver disease, Alisi, A., Nobili V., Ceccarelli S., Panera N., De Stefanis C., De Vito R., Vitali Roberta, Bedogni G., Balsano C., Cucchiara S., et al. , Expert Review of Molecular Diagnostics, Volume 14, Number 6, p.763-771, (2014)

Role of HMGB1 as a suitable biomarker of subclinical intestinal inflammation and mucosal healing in patients with inflammatory bowel disease, Palone, Francesca, Vitali Roberta, Cucchiara S., Pierdomenico Maria, Negroni Anna, Aloi M., Nuti F., Felice C., Armuzzi A., and Stronati L. , Inflammatory Bowel Diseases, Volume 20, Number 8, p.1448-1457, (2014)

Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice, Vitali, Roberta, Palone Francesca, Cucchiara S., Negroni Anna, Cavone L., Costanzo Manuela, Aloi M., Dilillo A., and Stronati L. , PLoS ONE, Volume 8, Number 6, p.e66527, (2013)

Characterization of adherent-invasive Escherichia coli isolated from pediatric patients with inflammatory bowel disease, Negroni, Anna, Costanzo Manuela, Vitali Roberta, Superti F., Bertuccini L., Tinari A., Minelli F., Di Nardo G., Nuti F., Pierdomenico Maria, et al. , Inflammatory Bowel Diseases, Volume 18, Number 5, p.913-924, (2012)

Fecal HMGB1 is a novel marker of intestinal mucosal inflammation in pediatric inflammatory bowel disease, Vitali, Roberta, Stronati L., Negroni Anna, Di Nardo G., Pierdomenico Maria, Del Giudice E., Rossi P., and Cucchiara S. , American Journal of Gastroenterology, Volume 106, Number 11, p.2029-2040, (2011)

New insights into the pathogenesis of inflammatory bowel disease: Transcription factors analysis in bioptic tissues from pediatric patients, Pierdomenico, Maria, Stronati L., Costanzo Manuela, Vitali Roberta, Di Nardo G., Nuti F., Oliva S., Cucchiara S., and Negroni Anna , Journal of Pediatric Gastroenterology and Nutrition, Volume 52, Number 3, p.271-279, (2011)